1379982-43-0

Basic information

• Product Name: 5-(4-chloropyrimidin-2ylamino)-2-methylbenzenesulfonamide
• Synonyms: 5-(4-chloropyrimidin-2ylamino)-2-methylbenzenesulfonamide
• CAS NO: 1379982-43-0
• Molecular Weight: 298.753
• Mol File: 1379982-43-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(4-chloropyrimidin-2ylamino)-2-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chloropyrimidin-2ylamino)-2-methylbenzenesulfonamide(1379982-43-0)
• EPA Substance Registry System: 5-(4-chloropyrimidin-2ylamino)-2-methylbenzenesulfonamide(1379982-43-0)

Safety Data

• Hazardous Substances Data: 1379982-43-0(Hazardous Substances Data)

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 
• 6973-09-7 5-amino-2-methylbenzenesulfonamide 

Downstream Products

• 635702-64-6 pazopanib hydrochloride 

Relevant articles and documents

MATERIALS AND METHODS FOR STRATIFYING AND TREATING CANCERS

The present invention relates to materials and methods for stratifying and treating cancers and to methods of identifying/selecting patients for treatment of cancer with tyrosine kinase inhibitors. Gene expression profiles, TP53 mutations and FGFR1 and PDGFRA expression are used to identify/select/stratify the cancers and patients.

A PROCESS FOR THE PREPARATION OF PAZOPANIB USING NOVEL INTERMEDIATE

The present invention provides a commercially viable process for preparing pazopanib and its pharmaceutically acceptable acid addition salts thereof in high yields using novel intermediate. The present invention also provides a process for the purificatio