1380243-43-5

Basic information

• Product Name: C₁₇H₁₆F₃NO₂
• Synonyms: C₁₇H₁₆F₃NO₂
• CAS NO: 1380243-43-5
• Molecular Weight: 323.315
• Mol File: 1380243-43-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₆F₃NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₆F₃NO₂(1380243-43-5)
• EPA Substance Registry System: C₁₇H₁₆F₃NO₂(1380243-43-5)

Safety Data

• Hazardous Substances Data: 1380243-43-5(Hazardous Substances Data)

Upstream product

• 1380243-31-1 C₁₈H₁₈F₃NOS 
• 1380243-22-0 C₁₂H₁₅NOS 
• 1380298-38-3 C₁₃H₁₉NO₄S₂ 
• 1303536-70-0 (S)-N-[1-hydroxy-4-(methylthio)butan-2-yl]benzamide 
• 98-88-4 benzoyl chloride 
• 10290-61-6 (S)-N-benzoylmethionine 

Downstream Products

• 654671-78-0 (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate 
• 1306610-49-0 C₂₃H₂₁F₆N₅O 
• 1380243-49-1 C₂₃H₁₉F₆N₅O₂ 
• 654671-78-0 sitagliptin phosphate 
• 1380243-46-8 C₁₇H₁₄F₃NO₃ 

Relevant articles and documents

INTERMEDIATES OF SITAGLIPTIN AND PREPARATION PROCESS THEREOF

Disclosed are intermediates of Sitagliptin, a preparation process thereof, and a process for synthesizing Sitagliptin using these intermediates. Sitagliptin is synthesized by using chiral amino compounds as a raw material, without having to build a chiral center with a chiral asymmetric catalytic hydrogenation, and high-pressure hydrogenation is avoided.