138038-92-3

Basic information

• Product Name: 1,3-bistri-isopropylsilyloxy-5-(7-geranyl-6-methoxy-2-benzofuranyl)benzene
• CAS NO: 138038-92-3
• Molecular Weight: 705.182
• Mol File: 138038-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-bistri-isopropylsilyloxy-5-(7-geranyl-6-methoxy-2-benzofuranyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bistri-isopropylsilyloxy-5-(7-geranyl-6-methoxy-2-benzofuranyl)benzene(138038-92-3)
• EPA Substance Registry System: 1,3-bistri-isopropylsilyloxy-5-(7-geranyl-6-methoxy-2-benzofuranyl)benzene(138038-92-3)

Safety Data

• Hazardous Substances Data: 138038-92-3(Hazardous Substances Data)

Upstream product

• 6138-90-5 trans-geranyl bromide 
• 112768-53-3 5-iodoresorcinol bis(triisopropylsilyl) ether 
• 138038-91-2 7-geranyl-6-methoxybenzofuran 

Downstream Products

• 79295-49-1 5-(7-(3,7-dimethylocta-2,6-dien-1-yl)-6-methoxybenzofuran-2-yl)benzene-1,3-diol 

Relevant articles and documents

Transition metal mediated synthesis of some prenylated phytoalexins of Morus alba Linn.

Directed functionalisation of resorcinol and benzofuran rings was achieved by activation with a coordinated tricarbonylchromium(O) unit and vicinal or remote lithiation directed by methoxy or t-butyldiphenylsilyloxy groups respectively. The process was applied either before [to the geranylbenzofuran (16) for mulberrofuran B (5)] or after [for moracin C (2)] palladium catalysed coupling of the 2-stannylated benzofuran and the 5-iodinated resorcinol moieties. In addition moracin I (14) was synthesised by a Stille coupling of the stannylated benzofuran (6) with the phloroglucinol triflate (14). Application to the synthesis of albafuran A (3) gave, unexpectedly, the 3-geranylbenzofuran (11).