1380671-78-2

Basic information

• Product Name: 2-[-6-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]imidazo[2,1-b][1,3,4]thiadiazole-2-[N-(dimethylaminomethino)] sulfonamido]-3-phenyl-1,3-thiazolidin-4-one
• CAS NO: 1380671-78-2
• Molecular Weight: 651.791
• Mol File: 1380671-78-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[-6-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]imidazo[2,1-b][1,3,4]thiadiazole-2-[N-(dimethylaminomethino)] sulfonamido]-3-phenyl-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[-6-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]imidazo[2,1-b][1,3,4]thiadiazole-2-[N-(dimethylaminomethino)] sulfonamido]-3-phenyl-1,3-thiazolidin-4-one(1380671-78-2)
• EPA Substance Registry System: 2-[-6-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]imidazo[2,1-b][1,3,4]thiadiazole-2-[N-(dimethylaminomethino)] sulfonamido]-3-phenyl-1,3-thiazolidin-4-one(1380671-78-2)

Safety Data

• Hazardous Substances Data: 1380671-78-2(Hazardous Substances Data)

Upstream product

• 68-11-1 mercaptoacetic acid 
• 88735-44-8 3-(2-bromoacetyl)-7-(diethylamino)-2H-chromen-2-one 
• 20571-42-0 7-diethylamino-2H-benzopyran-2-one 
• 17754-90-4 4-(Diethylamino)salicylaldehyde 
• 1380671-74-8 5-formyl-6-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]imidazo[2,1-b][1,3,4]thiadiazole-2-[N-(dimethylaminomethino)] sulfonamide 

Relevant articles and documents

Synthesis and evaluation of antibacterial and antitubercular activities of some novel imidazo[2,1-b][1,3,4]thiadiazole derivatives

A series of 2,5,6-trisubstituted imidazo[2,1-b][1,3,4]thiadiazoles were synthesized, structures of the compounds were elucidated and evaluated for antitubercular activity against Mycobacterium tuberculosis H37Rv using microplate alamar blue assay (MABA) method, antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Vibrio cholera, and Escherichia coli by broth micro dilution assay method. Some compounds exhibited significant antibacterial and antitubercular activities. Compounds 10, 14, and 15 emerged as the most active molecules, showed significant antimicrobial activity and may serve as leads for further optimization. Graphical Abstract: Synthesis, spectral studies, and antibacterial and antitubercular activities of a novel series of imidazo[2,1-b][1,3,4]thiadiazole derivatives are described[Figure not available: see fulltext.].