13826-86-3

Basic information

• Product Name: NITRONIUM TETRAFLUOROBORATE
• Synonyms: NITRONIUM TETRAFLUOROBORATE;NITRYL TETRAFLUOROBORATE;nitronium,tetrafluoroborate(1-);nitrylfluoborate;tetrafluoro-borate(1-nitryl;Nitronium tetrafluorborate;NITRONIUM TETRAFLUOROBORATE, 95+%;NITRONIUM TETRAFLUOROBORATE, 0.5M SOLUTI ON IN SULFOLANE
• CAS NO: 13826-86-3
• Molecular Formula: BF4NO2
• Molecular Weight: 132.81
• EINECS: 237-533-5
• Product Categories: C-X Bond Formation (Non-Halogen);Others;Synthetic Reagents;Electronic Chemicals;Micro/Nanoelectronics;halometallate salts
• Mol File: 13826-86-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 200 °C
• Appearance: white/crystal
• Density: 1.29 g/mL at 20 °C
• Storage Temp.: 2-8°C
• Solubility: Acetonitrile (Slightly, Heated)
• Water Solubility: Decomposes in water.
• Sensitive: Hygroscopic
• Stability: Stable, but may decompose in water on exposure to moist air. Incompatible with water, strong oxidizing agents.
• CAS DataBase Reference: NITRONIUM TETRAFLUOROBORATE(CAS DataBase Reference)
• NIST Chemistry Reference: NITRONIUM TETRAFLUOROBORATE(13826-86-3)
• EPA Substance Registry System: NITRONIUM TETRAFLUOROBORATE(13826-86-3)

Safety Data

• Hazard Codes: C
• Statements: 34-42/43-22-43-42
• Safety Statements: 26-36/37/39-45-23
• RIDADR: UN 3264 8/PG 2
• WGK Germany: 3
• RTECS: QX8620000
• F: 10-21
• TSCA: T
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 13826-86-3(Hazardous Substances Data)

Usage

Description

Nitronium tetrafluoroborate, also known as NOBF4, is a colorless crystalline solid that is widely used in various chemical reactions and processes due to its unique properties. It is a powerful nitrating and fluorinating agent, which makes it a valuable compound in the field of organic chemistry.

Uses

Used in Pharmaceutical Industry:
Nitronium tetrafluoroborate is used as a nitrating agent for the preparation of triazolyl glycoside, which serves as a galectin-3 inhibitor. Galectin-3 inhibitors have potential applications in the treatment of various diseases, including cancer, fibrosis, and inflammatory disorders. The use of NOBF4 in this context highlights its importance in the development of novel therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, nitronium tetrafluoroborate is utilized as a nitrating agent for the synthesis of various organic compounds. Its ability to selectively nitrate specific functional groups makes it a preferred choice for many chemists working on complex molecular structures.
Used in Fluorination Reactions:
Nitronium tetrafluoroborate is also employed as a fluorinating agent in organic chemistry. The introduction of fluorine atoms into organic molecules can significantly alter their properties, such as reactivity, stability, and biological activity. NOBF4 is a versatile reagent for these fluorination reactions, contributing to the development of new compounds with improved characteristics.

InChI:InChI=1/BF4.NO2/c2-1(3,4)5;2-1-3/q-1;+1