1383026-42-3Relevant articles and documents
Synthetic method for sacubitril intermediate
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, (2019/03/28)
The invention relates to a synthetic method for a sacubitril intermediate and aims at solving the technical problems of expensive reagents, harsh reaction conditions, low yield and the like of the existing synthetic method. The synthetic method provided b
NEPRILYSIN INHIBITORS
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, (2015/08/04)
In one aspect, the invention relates to compounds having the formula I: where R1-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
NEPRILYSIN INHIBITORS
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, (2014/03/21)
In one aspect, the invention relates to compounds having the formula: where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs