1383616-98-5

Basic information

• Product Name: (1S,2R)-tBu(OH)(C₆H₃)CHN(CHPh)2OH
• Synonyms: (1S,2R)-tBu(OH)(C₆H₃)CHN(CHPh)2OH
• CAS NO: 1383616-98-5
• Molecular Weight: 373.495
• Mol File: 1383616-98-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2R)-tBu(OH)(C₆H₃)CHN(CHPh)2OH(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-tBu(OH)(C₆H₃)CHN(CHPh)2OH(1383616-98-5)
• EPA Substance Registry System: (1S,2R)-tBu(OH)(C₆H₃)CHN(CHPh)2OH(1383616-98-5)

Safety Data

• Hazardous Substances Data: 1383616-98-5(Hazardous Substances Data)

Upstream product

• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 2725-53-3 2-hydroxy-5-t-butylbenzaldehyde 

Relevant articles and documents

Titanium complexes of chiral amino alcohol derived Schiff bases as efficient catalysts in asymmetric oxidation of prochiral sulfides with hydrogen peroxide as an oxidant

An efficient asymmetric oxidation of prochiral sulfides catalyzed by a series of simple in situ generated complexes based on chiral amino alcohol derived Schiff bases with Ti(Oi-Pr)4 was carried out in presence of cheap and environmentally benign oxidant H2O2 at 0 °C. Prochiral sulfides were converted to respective chiral sulfoxides efficiently (conversion, 93%; up to ee, 98%) with this system in 10 h at 0 °C. The present study demonstrated a significant role of steric influence of the substituent attached on both aryl and alkyl moiety on the enantioselectivity. Kinetic studies of the catalytic reaction showed first order dependence on substrate and catalyst whereas it is zero for the oxidant. Kinetic studies in combination with UV-vis. spectral studies were used to propose a catalytic cycle for the sulfoxidation reaction.