1383674-64-3

Basic information

• Product Name: 2,2'-(6-oxo-1-(1-phenylethyl)-1,6-dihydropyridazine-4,5-diyl)dibenzonitrile
• Synonyms: 2,2'-(6-oxo-1-(1-phenylethyl)-1,6-dihydropyridazine-4,5-diyl)dibenzonitrile
• CAS NO: 1383674-64-3
• Molecular Weight: 402.455
• Mol File: 1383674-64-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2'-(6-oxo-1-(1-phenylethyl)-1,6-dihydropyridazine-4,5-diyl)dibenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-(6-oxo-1-(1-phenylethyl)-1,6-dihydropyridazine-4,5-diyl)dibenzonitrile(1383674-64-3)
• EPA Substance Registry System: 2,2'-(6-oxo-1-(1-phenylethyl)-1,6-dihydropyridazine-4,5-diyl)dibenzonitrile(1383674-64-3)

Safety Data

• Hazardous Substances Data: 1383674-64-3(Hazardous Substances Data)

Upstream product

• 1383674-70-1 2-(5-chloro-6-oxo-1-(1-phenylethyl)-1,6-dihydropyridazin-4-yl)benzonitrile 
• 214360-48-2 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 

Relevant articles and documents

DIARYLPYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF FOR THE TREATMENT OF HUMANS

The present invention relates to diarylpyridazinone derivatives that block the potassium Kv channels (specifically the Kv1.5, Kv4.3, and Kv11.1 channels) and to the use thereof for the treatment of humans. Said compounds have the general formula (I), where R1 and R2 are simultaneously or independently one or more groupings such as: halogen, such as F, Br, Cl, a straight or branched C1-C4 alkyl, hydroxy, a straight or branched C1-C4 alkoxy, arylsulfonamido, in which the aryl is optionally replaced with a straight or branched C1-C4 alkyl, or nitrile, as well as the various enantiomers and the mixtures thereof in any proportion, and the pharmaceutically acceptable salts thereof.