1383747-11-2

Basic information

• Product Name: 4-{[(1S,2R)-2-(tert-Butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]methoxy}-1-ethyl-3-methyl-1H-pyrazole
• Synonyms: 4-{[(1S,2R)-2-(tert-Butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]methoxy}-1-ethyl-3-methyl-1H-pyrazole
• CAS NO: 1383747-11-2
• Molecular Weight: 542.769
• Mol File: 1383747-11-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{[(1S,2R)-2-(tert-Butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]methoxy}-1-ethyl-3-methyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(1S,2R)-2-(tert-Butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]methoxy}-1-ethyl-3-methyl-1H-pyrazole(1383747-11-2)
• EPA Substance Registry System: 4-{[(1S,2R)-2-(tert-Butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]methoxy}-1-ethyl-3-methyl-1H-pyrazole(1383747-11-2)

Safety Data

• Hazardous Substances Data: 1383747-11-2(Hazardous Substances Data)

Upstream product

• 1383746-99-3 1-ethyl-3-methyl-1H-pyrazol-4-ol 
• 1369767-21-4 {(1S,2R)-[2-(tert-butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]}methanol 
• 1369767-20-3 ((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol 
• 528587-70-4 (1S,5R)-2-oxo-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexane 
• 501-00-8 3-fluorophenylacetonitrile 

Downstream Products

• 1383747-14-5 (1R,2S)-2-[(1-ethyl-3-methyl-1H-pyrazol-4-yl)oxymethyl]-2-(3-fluorophenyl)cyclopropanecarboxylic acid 
• 1383747-12-3 {(1R,2S)-2-[(1-Ethyl-3-methyl-1H-pyrazol-4-yl)oxymethyl]-2-(3-fluorophenyl)cyclopropyl}methanol 
• 1383747-13-4 (1R,2 S)-2-[(1-Ethyl-3-methyl-1H-pyrazol-4-yl)oxymethyl]-2-(3-fluorophenyl)cyclopropanecarbaldehyde 

Relevant articles and documents

CYCLOPROPANE DERIVATIVES

A cyclopropane derivative represented by the following formula (I) or a pharmaceutically acceptable salt thereof has orexin receptor inhibitory action, and thus, is extremely useful as an agent for preventing or treating sleep disorder or dyssomnia caused by orexin, including insomnia as a typical example: wherein A1, A2 and A3 each independently represent an aryl group, a heterocyclyl group or the like, R1, R2 and R3 each independently represent a hydrogen atom, a C1-6 alkyl group or the like, X represents an oxygen atom or the like, and L represents a bond or the like.