1385018-21-2

Basic information

• Product Name: (Z)-5-benzylidene-2-methyl-4-oxocyclopent-1-en-1-yl acetate
• CAS NO: 1385018-21-2
• Molecular Weight: 242.274
• Mol File: 1385018-21-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-5-benzylidene-2-methyl-4-oxocyclopent-1-en-1-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-5-benzylidene-2-methyl-4-oxocyclopent-1-en-1-yl acetate(1385018-21-2)
• EPA Substance Registry System: (Z)-5-benzylidene-2-methyl-4-oxocyclopent-1-en-1-yl acetate(1385018-21-2)

Safety Data

• Hazardous Substances Data: 1385018-21-2(Hazardous Substances Data)

Upstream product

• 78-80-8 2-methylbut-1-en-3-yne 
• 137935-62-7 methyl-4 phenyl-1 penten-4 yn-2 ol-1 
• 878549-71-4 4-methyl-1-phenylpent-4-en-2-yn-1-yl acetate 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Diastereoselective [4 + 1] Cycloaddition of Alkenyl Propargyl Acetates with CO Catalyzed by [RhCl(CO)2]2

A class of alkenyl propargyl acetates, RCH(OAc)C≡CC(CH 3)=CH2 (5), are found to undergo [4 + 1] cycloaddition with CO (1 atm) in the presence of [RhCl(CO)2]2 in refluxing 1,2-dichloroethane to give cyclopentenones (6) in good yields. It has been demonstrated that, when the R group of 5 is a phenyl group bearing o-electron-withdrawing substituents, up to 10:1 diastereoselectivity and 96% yield can be achieved for the [4 + 1] cycloaddition. This process provides a convenient method to construct highly functionalized cyclopentenones that are useful in organic synthesis.