138714-53-1

Basic information

• Product Name: 2,3-DIOXO-3-PHENYL-PROPIONIC ACID TERT-BUTYL ESTER
• Synonyms: 2,3-DIOXO-3-PHENYL-PROPIONIC ACID TERT-BUTYL ESTER;tert-Butyl 2,3-dioxo-3-phenylpropanoate
• CAS NO: 138714-53-1
• Molecular Formula: C₁₃H₁₄O₄
• Molecular Weight: 234.25
• Mol File: 138714-53-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-DIOXO-3-PHENYL-PROPIONIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIOXO-3-PHENYL-PROPIONIC ACID TERT-BUTYL ESTER(138714-53-1)
• EPA Substance Registry System: 2,3-DIOXO-3-PHENYL-PROPIONIC ACID TERT-BUTYL ESTER(138714-53-1)

Safety Data

• Hazardous Substances Data: 138714-53-1(Hazardous Substances Data)

Usage

General Description

2,3-Dioxo-3-phenyl-propionic acid tert-butyl ester, also known as methyl 2,3-dioxo-3-phenylpropanoate, is a chemical compound with the molecular formula C13H14O4. It is a colorless to pale yellow liquid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,3-DIOXO-3-PHENYL-PROPIONIC ACID TERT-BUTYL ESTER is also used as a reagent in organic synthesis and as a flavoring agent in food products. It is important to handle this compound with caution as it may cause irritation to the skin, eyes, and respiratory system. Additionally, it should be stored in a cool, dry place away from incompatible materials.

Upstream product

• 98-88-4 benzoyl chloride 
• 107-59-5 tert-Butyl chloroacetate 
• 5397-27-3 tert-butyl 3-hydroxy-3-phenylpropionate 
• 138714-59-7 t-butyl 3-oxo-(2-triphenylphosphoranylidine)-3-phenylpropionate 
• 35000-37-4 (tert-butyloxycarbonylmethyl)triphenylphosphonium chloride 
• 86302-43-4 (tert-Butoxycarbonylmethylene)triphenylphosphorane 

Downstream Products

• 138732-29-3 1-Benzyl-4-isopropyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Acceleration of the Dess-Martin Oxidation by Water

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SYNTHESIS AND CHARACTERIZATION OF PYRROLINONECARBOXYLATES FORMED BY REACTION OF VICINAL TRICARBONYL DERIVATIVES WITH ALDEHYDE SCHIFF BASES

A series of vicinal tricarbonyl derivatives undergo reaction with aldehyde Schiff bases forming pyrrolinone derivatives by benzilic acid-related rearrangements.The structures were established by X-ray analyses and, independently by the SESAMI NMR-based computer program.

BENZILIC ACID REARRANGEMENTS IN THE REACTIONS OF ARYL VICINAL TRICARBONYL DERIVATIVES WITH ALDEHYDE SCHIFF BASES

Reactions of aryl and hetero vicinal tricarbonyl derivatives with aldehyde Schiff bases of the general structure RCH2CHO lead to pyrrolinone derivatives by benzilic acid-related rearrangements, driven, most probably, by iminium ion intermediates.