13877-55-9 Usage
General Description
7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO- is a chemical compound that belongs to the class of pyrazolopyrimidine derivatives. It is a heterocyclic organic compound with a molecular formula of C7H8N4O. 7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, 1,4-DIHYDRO- is a potent inhibitor of the enzyme dihydroorotate dehydrogenase (DHODH) and has shown potential as an antiviral and anticancer agent. Its structure and properties make it a promising candidate for further research and development in the fields of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 13877-55-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,7 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13877-55:
(7*1)+(6*3)+(5*8)+(4*7)+(3*7)+(2*5)+(1*5)=129
129 % 10 = 9
So 13877-55-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H2N4O/c10-5-4-3(1-8-9-4)6-2-7-5/h1-2H
13877-55-9Relevant articles and documents
Pyrazolo pyrimidines useful as aurora kinase inhibitors
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Page/Page column 84-85, (2010/11/25)
The present invention provides compounds having the formula: wherein A-B together represent one of the following structures: wherein one of is a double bond, as valency permits; and R2, R4, X1A, X2A, X1B, X2B, L1, L2, Y and Z are as defined in classes and subclasses herein, and pharmaceutical compositions thereof, as described generally and in subclasses herein, which compounds are useful as inhibitors of protein kinase (e.g., Aurora), and thus are useful, for example, for the treatment of Aurora mediated diseases.