1388224-20-1

Basic information

• Product Name: C₃₆H₄₂F₂N₆O₄
• CAS NO: 1388224-20-1
• Molecular Weight: 660.764
• Mol File: 1388224-20-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₂F₂N₆O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₂F₂N₆O₄(1388224-20-1)
• EPA Substance Registry System: C₃₆H₄₂F₂N₆O₄(1388224-20-1)

Safety Data

• Hazardous Substances Data: 1388224-20-1(Hazardous Substances Data)

Upstream product

• 1007882-23-6 methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate 

Relevant articles and documents

Synthesis and evaluation of novel potent HCV NS5A inhibitors

Judicious modifications to the structure of the previously reported HCV NS5A inhibitor 1, resulted in more potent anti-HCV compounds with similar and in some cases improved toxicity profiles. The synthesis of 19 new NS5A inhibitors is reported along with their ability to block HCV replication in an HCV 1b replicon system. For the most potent compounds chemical stability, stability in liver microsomes and inhibition of relevant CYP450 enzymes is also presented.