138883-24-6

Basic information

• Product Name: ethyl 2-(2-aminothiazol-4-yl)-2-p-tosyloxyiminoacetate
• Synonyms: ethyl 2-(2-aminothiazol-4-yl)-2-p-tosyloxyiminoacetate
• CAS NO: 138883-24-6
• Molecular Weight: 369.422
• Mol File: 138883-24-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-(2-aminothiazol-4-yl)-2-p-tosyloxyiminoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-aminothiazol-4-yl)-2-p-tosyloxyiminoacetate(138883-24-6)
• EPA Substance Registry System: ethyl 2-(2-aminothiazol-4-yl)-2-p-tosyloxyiminoacetate(138883-24-6)

Safety Data

• Hazardous Substances Data: 138883-24-6(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 60845-81-0 ethyl 2-amino-α-(hydroxyimino)-4-thiazole acetate 

Downstream Products

• 138883-30-4 [5-Benzylsulfanyl-2-(trityl-amino)-thiazol-4-yl]-oxo-acetic acid ethyl ester 
• 138883-31-5 [5-Methoxycarbonylmethylsulfanyl-2-(trityl-amino)-thiazol-4-yl]-oxo-acetic acid ethyl ester 
• 138883-29-1 [5-Ethylsulfanyl-2-(trityl-amino)-thiazol-4-yl]-oxo-acetic acid ethyl ester 
• 4124-42-9 monoammonium para-toluenesulfonate 
• 138883-26-8 ethyl 2-(5-ethylthio-2-aminothiazol-4-yl)-2-oxoacetate 
• 138883-27-9 ethyl 2-(5-benzylthio-2-aminothiazol-4-yl)-2-oxoacetate 
• 138883-28-0 (2-Amino-5-methoxycarbonylmethylsulfanyl-thiazol-4-yl)-oxo-acetic acid ethyl ester 
• 138883-25-7 ethyl 2-(2-tritylaminothiazol-4-yl)-2-p-tosyloxyiminoacetate 
• 145221-25-6 ethyl 2-(2-acetylaminothiazol-4-yl)-2-p-tosyloxyiminoacetate 

Relevant articles and documents

Reaction of aminothiazole-oximetosylates with thiols

The reaction of ethyl 2-(2-aminothiazol-4-yl)-2-tosyloxyiminoacetate and its tritylamino analogue with thiols gave ethyl 2-(5-R-thio-2-amino- or tritylamino-thiazol-4-yl)-2-oxoacetate derivatives. Structures were elucidated by ir, 1H-, 13C-nmr and mass spectroscopy. A reaction mechanism is suggested.