1390630-97-3

Basic information

• Product Name: (Z)-N-(2-iodophenyl)-N,2-dimethyl-3-phenylacrylamide
• Synonyms: (Z)-N-(2-iodophenyl)-N,2-dimethyl-3-phenylacrylamide
• CAS NO: 1390630-97-3
• Molecular Weight: 377.225
• Mol File: 1390630-97-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-N-(2-iodophenyl)-N,2-dimethyl-3-phenylacrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-(2-iodophenyl)-N,2-dimethyl-3-phenylacrylamide(1390630-97-3)
• EPA Substance Registry System: (Z)-N-(2-iodophenyl)-N,2-dimethyl-3-phenylacrylamide(1390630-97-3)

Safety Data

• Hazardous Substances Data: 1390630-97-3(Hazardous Substances Data)

Upstream product

• 1199-77-5 α-methylcinnamic acid 
• 7042-33-3 ethyl 2-methylcinnamate 

Relevant articles and documents

Domino carbopalladation-cross-coupling for the synthesis of 3,3-disubstituted oxindoles

This study examines a domino carbopalladation-cross-coupling reaction for the formation of valuable oxindole scaffolds. Furthermore, the reaction sequence forges vicinal stereocenters in a stereospecific manner through the formation of two carbon-carbon bonds and, thereby, rapidly generates complexity. The reaction gives high yields for a variety of acrylamide substrates, and various organoboranes have also been evaluated for the cross-coupling. This work offers insight into the relative rates determining a successful carbopalladation-cross- coupling reaction and how to favor the desired reaction pathway.