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13907-53-4

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13907-53-4 Usage

General Description

1-(2-chloroethyl)-3-naphthalen-2-yl-1-nitrosourea, also known as nimustine or ACNU, is a nitrosourea derivative chemical compound that is used as an antineoplastic agent and alkylating agent. It has been used in the treatment of various types of cancer, including brain tumors, lung cancer, and advanced melanoma. Nimustine works by inhibiting DNA and RNA synthesis, ultimately leading to cell death in cancerous cells. It has been shown to have some efficacy in crossing the blood-brain barrier, making it particularly useful in treating brain tumors. However, it can also cause toxic effects, including myelosuppression, nausea, and vomiting. Overall, nimustine is a powerful chemotherapeutic agent that is used in the treatment of certain cancers, but it also comes with potential risks and side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 13907-53-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13907-53:
(7*1)+(6*3)+(5*9)+(4*0)+(3*7)+(2*5)+(1*3)=104
104 % 10 = 4
So 13907-53-4 is a valid CAS Registry Number.

13907-53-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-naphthalen-2-yl-1-nitrosourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13907-53-4 SDS

13907-53-4Downstream Products

13907-53-4Relevant articles and documents

The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.

Johnston,McCaleb,Opliger,Montgomery

, p. 892 - 911 (2007/10/05)

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