1391868-27-1Relevant articles and documents
Synthesis of acrylonitriles through an FeCl3-catalyzed domino propargylic substitution/aza-Meyer-Schuster rearrangement sequence
Hao, Lu,Wu, Feng,Ding, Zong-Cang,Xu, Su-Xia,Ma, Yan-Li,Chen, Li,Zhan, Zhuang-Ping
supporting information; experimental part, p. 6453 - 6456 (2012/06/15)
Nontoxic cyanide source: An unprecedented route to acrylonitriles by employing propargylic alcohols and para-tolylsulfonohydrazide as a combined cyano source has been developed (see scheme). This efficient and practical cyanation reaction proceeds through an FeCl3-catalyzed domino propargylic substitution/aza-Meyer-Schuster rearrangement sequence, the rearrangement process of which is reported for the first time. Copyright