1392101-11-9

Basic information

• Product Name: C₁₂₂H₁₇₃N₂₅O₁₇
• CAS NO: 1392101-11-9
• Molecular Weight: 2261.87
• Mol File: 1392101-11-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂₂H₁₇₃N₂₅O₁₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂₂H₁₇₃N₂₅O₁₇(1392101-11-9)
• EPA Substance Registry System: C₁₂₂H₁₇₃N₂₅O₁₇(1392101-11-9)

Safety Data

• Hazardous Substances Data: 1392101-11-9(Hazardous Substances Data)

Upstream product

• 92122-45-7 Fmoc-D-Lys(BOC)-OH 
• 108-24-7 acetic anhydride 
• 86123-10-6 Fmoc-D-Phe-OH 

Relevant articles and documents

Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: A comparative study of different backbones

Novel remedies in the battle against multidrug-resistant bacterial strains are urgently needed, and one obvious approach involves antimicrobial peptides and mimics hereof. The impact of α- and β-peptoid as well as β3-amino acid modifications on the activity profile against β-lactamase-producing Escherichia coli was assessed by testing an array comprising different types of cationic peptidomimetics obtained by a general monomer-based solid-phase synthesis protocol. Most of the peptidomimetics possessed high to moderate activity toward multidrug-resistant E. coli as opposed to the corresponding inactive peptides. Nevertheless, differences in hemolytic activities indicate that a careful choice of backbone design constitutes a significant parameter in the search for effective cationic antimicrobial peptidomimetics targeting specific bacteria.