139261-90-8 Usage
Description
PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE, also known as 3-Benzoyl-1-tosylpyrrole, is a chemical compound that serves as an intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique molecular structure, which includes a phenyl group, a tosyl group, and a pyrrole ring.
Uses
Used in Pharmaceutical Industry:
PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE is used as an intermediate in the synthesis of rac Ketorolac 6-Benzoyl Isomer (K235620) for the pharmaceutical industry. PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE plays a crucial role in the production of Ketorolac EP Impurity C, which is an isomeric impurity of Ketorolac (K235620). The synthesis of this intermediate allows for the development and manufacturing of medications that can be used for various therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 139261-90-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,2,6 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 139261-90:
(8*1)+(7*3)+(6*9)+(5*2)+(4*6)+(3*1)+(2*9)+(1*0)=138
138 % 10 = 8
So 139261-90-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H15NO3S/c1-14-7-9-17(10-8-14)23(21,22)19-12-11-16(13-19)18(20)15-5-3-2-4-6-15/h2-13H,1H3
139261-90-8Relevant articles and documents
Acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions: evidence for organoaluminum intermediates
Huffman, John W.,Smith, Valerie J.,Padgett, Lea W.
, p. 2104 - 2112 (2008/09/18)
The Friedel-Crafts acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions has been reinvestigated. Evidence is presented in support of the hypothesis that when AlCl3 is used as the Lewis acid, acylation proceeds via reaction of
3-ACYL-1-TOSYLPYRROLES AS EXCELLENT PRECURSORS OF 3-VINYLIDENEPYRROLES
Settambolo, Roberta,Mazzetti, Michele,Pini, Dario,Pucci, Sergio,Lazzaroni, Raffaello
, p. 173 - 176 (2007/10/02)
Two simple general methods for the synthesis of 3-vinylidenepyrroles 4a - c both starting from 3-acyl-1-tosylpyrroles have been developed.The simplest term of this class, 3-(1-methylethenyl)pyrrole, 4a, and the congeners 3-(1-phenylethenyl)pyrrole, 4b, an