139305-96-7 Usage
Description
(S)-1-(3-Bromophenyl)ethylamine is an organic compound that features a bromophenyl group attached to an ethylamine backbone. It is a chiral molecule with the (S) configuration, which means it has a specific three-dimensional arrangement of atoms in its structure. (S)-1-(3-Bromophenyl)ethylamine is significant in the field of organic chemistry and pharmaceuticals due to its potential applications in the synthesis of various molecules.
Uses
Used in Pharmaceutical Industry:
(S)-1-(3-Bromophenyl)ethylamine is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure allows it to be a key component in the creation of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
(S)-1-(3-Bromophenyl)ethylamine is used as a reactant in the Ullmann coupling reaction with N-H containing heteroarenes, utilizing copper iodide as a catalyst. This reaction is an important method for forming carbon-carbon and carbon-heteroatom bonds, which are crucial in the synthesis of complex organic molecules and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 139305-96-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,0 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 139305-96:
(8*1)+(7*3)+(6*9)+(5*3)+(4*0)+(3*5)+(2*9)+(1*6)=137
137 % 10 = 7
So 139305-96-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H10BrN/c1-6(10)7-3-2-4-8(9)5-7/h2-6H,10H2,1H3/t6-/m0/s1
139305-96-7Relevant articles and documents
Enantioselective enzymatic acylation of 1-(3′-bromophenyl)ethylamine
Gill, Iqbal I.,Das, Jagbandhu,Patel, Ramesh N.
, p. 1330 - 1337 (2007)
An efficient biocatalytic process has been developed for the resolution of 1-(3′-bromophenyl)ethylamine (RS)-1 by way of enantioselective lipase-mediated (R)-selective acylation with ethyl 2-methoxyacetate to afford (S)-amine (S)-1 and (R)-2″-methoxyaceta
Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases
Galman, James L.,Slabu, Iustina,Weise, Nicholas J.,Iglesias, Cesar,Parmeggiani, Fabio,Lloyd, Richard C.,Turner, Nicholas J.
supporting information, p. 361 - 366 (2017/08/14)
The discovery and characterisation of enzymes with both monoamine and diamine transaminase activity is reported, allowing conversion of a wide range of target ketone substrates with just a small excess of amine donor. The diamine co-substrates (putrescine, cadaverine or spermidine) are bio-derived and the enzyme system results in very little waste, making it a greener strategy for the production of valuable amine fine chemicals and pharmaceuticals.
PROCESS FOR THE PREPARATION OF CHIRAL AMINES FROM PROCHIRAL KETONES
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Page/Page column 5; 6; 7, (2015/12/11)
There is provided a method for the preparation of an enantiomerically enriched amine from a prochiral ketone.