1393094-72-8

Basic information

• Product Name: C₂₂H₂₃NO₇S
• CAS NO: 1393094-72-8
• Molecular Weight: 445.493
• Mol File: 1393094-72-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₃NO₇S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₃NO₇S(1393094-72-8)
• EPA Substance Registry System: C₂₂H₂₃NO₇S(1393094-72-8)

Safety Data

• Hazardous Substances Data: 1393094-72-8(Hazardous Substances Data)

Upstream product

• 1210801-41-4 dimethyl 2-[2-(4-methylphenylsulfonamido)phenyl]malonate 
• 1423-60-5 methyl ethynyl ketone 

Relevant articles and documents

Chiral aminophosphines as catalysts for enantioselective double-michael indoline syntheses

The bisphosphine-catalyzed double-Michael addition of dinucleophiles to electron-deficient acetylenes is an efficient process for the synthesis of many nitrogencontaining heterocycles. Because the resulting heterocycles contain at least one stereogenic center, this double-Michael reaction would be even more useful if an asymmetric variant of the reaction were to be developed. Aminophosphines can also facilitate the double-Michael reaction and chiral amines are more readily available in Nature and synthetically; therefore, in this study we prepared several new chiral aminophosphines. When employed in the asymmetric double-Michael reaction between ortho-tosylamidophenyl malonate and 3-butyn-2-one, the chiral aminophosphines produced indolines in excellent yields with moderate asymmetric induction.