139313-77-2

Basic information

• Product Name: (5-Chloro-benzofuran-3-yl)-acetonitrile
• Synonyms: (5-Chloro-benzofuran-3-yl)-acetonitrile
• CAS NO: 139313-77-2
• Molecular Weight: 191.617
• Mol File: 139313-77-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5-Chloro-benzofuran-3-yl)-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Chloro-benzofuran-3-yl)-acetonitrile(139313-77-2)
• EPA Substance Registry System: (5-Chloro-benzofuran-3-yl)-acetonitrile(139313-77-2)

Safety Data

• Hazardous Substances Data: 139313-77-2(Hazardous Substances Data)

Upstream product

• 3261-05-0 5-chlorobenzofuran-3(2H)-one 
• 2537-48-6 diethyl 1-cyanomethylphosphonate 

Relevant articles and documents

Antihyperglycemic activity of novel substituted 3H-1,2,3,5-oxathiadiazole 2-oxides

A series of substituted 3H-1,2,3,5-oxathiadiazole-2-oxides (6) was prepared and tested for antihyperglycemic activity in the db/db mouse, a model for type 2 (non-insulin dependent) diabetes mellitus. The oxathiadiazoles 6 were synthesized by a two-step sequence: treatment of a substituted acetonitrile (4) with hydroxylamine to give the corresponding amidoxime (5) and cyclization with thionyl chloride to yield 6. In terms of potency, the 2-naphthalenylmethyl group (as in compound 3) was found to be the optimal substituent in this series. Compound 3 was approximately 5 times more potent than ciglitazone (1).