1393604-40-4Relevant articles and documents
Topological study of mechanistic diversity in conjugated fatty acid biosynthesis
Bhar, Palash,Reed, Darwin W.,Covello, Patrick S.,Buist, Peter H.
, p. 6686 - 6690 (2012/08/27)
Variations on an oxidative theme: The precision with which FAD2-type desaturases carry out C-H activation reactions on flexible lipidic substrates is astonishing. The conformational space available within the active site of these enzymes has been explored using deuterium-labeled substrates, and evidence for a novel quasi-eclipsed conformer has been uncovered. The scheme shows some prototypical substrate conformations. Copyright