1393815-12-7Relevant articles and documents
Interactions of non-polar and click-able nucleotides in the confines of a DNA polymerase active site
Obeid, Samra,Busskamp, Holger,Welte, Wolfgang,Diederichs, Kay,Marx, Andreas
supporting information, p. 8320 - 8322 (2012/10/29)
Modified nucleotides play a paramount role in many cutting-edge biomolecular techniques. The present structural study highlights the plasticity and flexibility of the active site of a DNA polymerase while incorporating non-polar Click-able nucleotide analogs and emphasizes new insights into rational design guidelines for modified nucleotides.