1395026-84-2

Basic information

• Product Name: 3-(2-chlorophenyl)-7-(methylthio)-2-(2-oxopropylamino)pyrimido[4,5-d]pyrimidin-4(3H)-one
• Synonyms: 3-(2-chlorophenyl)-7-(methylthio)-2-(2-oxopropylamino)pyrimido[4,5-d]pyrimidin-4(3H)-one
• CAS NO: 1395026-84-2
• Molecular Weight: 375.838
• Mol File: 1395026-84-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-chlorophenyl)-7-(methylthio)-2-(2-oxopropylamino)pyrimido[4,5-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-chlorophenyl)-7-(methylthio)-2-(2-oxopropylamino)pyrimido[4,5-d]pyrimidin-4(3H)-one(1395026-84-2)
• EPA Substance Registry System: 3-(2-chlorophenyl)-7-(methylthio)-2-(2-oxopropylamino)pyrimido[4,5-d]pyrimidin-4(3H)-one(1395026-84-2)

Safety Data

• Hazardous Substances Data: 1395026-84-2(Hazardous Substances Data)

Upstream product

• 298-08-8 glycine methyl ketone 
• 1395026-24-0 2-chloro-3-(2-chlorophenyl)-7-(methylthio)pyrimido[4,5-d]pyrimidin-4(3H)-one 
• 3320-83-0 o-chlorophenyl isocyanate 
• 776-53-4 ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate 

Downstream Products

• 1395026-86-4 4-(2-Chloro-phenyl)-8-methanesulfinyl-1-methyl-4H-3,4,7,9,9b-pentaaza-cyclopenta[a]naphthalen-5-one 
• 1395026-85-3 4-(2-Chloro-phenyl)-1-methyl-8-methylsulfanyl-4H-3,4,7,9,9b-pentaaza-cyclopenta[a]naphthalen-5-one 
• 1395026-83-1 6-(2-chlorophenyl)-9-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one trifluoroacetate 

Relevant articles and documents

TRICYCLIC INHIBITORS OF KINASES

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein X, Y, Z, R3 and R4 are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as wee-1 and methods of treating diseases such as cancer.