1395085-48-9

Basic information

• Product Name: ethyl 2-amino-4-methyl-6-(4-methylphenyl)pyrimidine-5-carboxylate
• Synonyms: ethyl 2-amino-4-methyl-6-(4-methylphenyl)pyrimidine-5-carboxylate
• CAS NO: 1395085-48-9
• Molecular Weight: 271.319
• Mol File: 1395085-48-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 2-amino-4-methyl-6-(4-methylphenyl)pyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-4-methyl-6-(4-methylphenyl)pyrimidine-5-carboxylate(1395085-48-9)
• EPA Substance Registry System: ethyl 2-amino-4-methyl-6-(4-methylphenyl)pyrimidine-5-carboxylate(1395085-48-9)

Safety Data

• Hazardous Substances Data: 1395085-48-9(Hazardous Substances Data)

Upstream product

• 299949-24-9 ethyl 6-methyl-2-oxo-4-p-tolyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 104-87-0 4-methyl-benzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 1245716-49-7 ethyl 4-methyl-6-p-tolyl-2-(tosyloxy)pyrimidine-5-carboxylate 
• 1395085-50-3 C₁₆H₁₈N₄O₂ 

Relevant articles and documents

Heterogenized hybrid catalyst of 1-sulfonic acid-3-methyl imidazolium ferric chloride over NaY zeolite for one-pot synthesis of 2-amino-4-arylpyrimidine derivatives: A viable approach

A new hybrid material of NaY zeolite supported 1-sulfonic acid-3-methyl imidazolium ferric chloride [Msim][FeCl4] has been developed by modifying the zeolite surface with six different w/w ratios through wet impregnation method. These composite

One-pot synthesis of 4-aryl-2-cyanoimino-3,4-dihydro-1h-pyrimidines and their reactions

A series of 4-aryl-2-cyanoimino-3,4-dihydro-1H-pyrimidines was obtained as a result of a multicomponent Biginelli reaction using 1,3-dicarbonyl compounds, aromatic aldehydes, and cyanamide. Alkylation of the obtained compounds with benzyl chloride takes place at the two nitrogen atoms of the tetrahydropyrimidine ring, while oxidation with manganese dioxide leads to the corresponding 1-(pyrimidin-2-yl)carbamides or pyrimidine-2-amines, depending on the conditions.