139577-59-6

Basic information

• Product Name: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methyl-1-buten yl]benzoyl]-, dimethyl ester, (E)-
• CAS NO: 139577-59-6
• Molecular Formula: C23H29N5O6
• Molecular Weight: 471.513
• Mol File: 139577-59-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methyl-1-buten yl]benzoyl]-, dimethyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methyl-1-buten yl]benzoyl]-, dimethyl ester, (E)-(139577-59-6)
• EPA Substance Registry System: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methyl-1-buten yl]benzoyl]-, dimethyl ester, (E)-(139577-59-6)

Safety Data

• Hazardous Substances Data: 139577-59-6(Hazardous Substances Data)

Upstream product

• 139577-57-4 methyl 4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-2-en-2-yl>benzoate 
• 139577-56-3 methyl 4-(6-carboethoxy-6-cyanohex-2-en-2-yl)benzoate 
• 136527-53-2 methyl 4-(5-acetoxypent-1-en-2-yl)benzoate 
• 139577-55-2 methyl 4-(5-iodopent-2-en-2-yl)benzoate 
• 139577-54-1 methyl 4-(5-iodopent-1-en-2-yl)benzoate 
• 136527-54-3 methyl 4-(5-hydroxypent-1-en-2-yl)benzoate 
• 23150-65-4 L-glutamic dimethyl ester hydrochloride 
• 139577-58-5 4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-2-en-2-yl>benzoic acid 

Downstream Products

• 139577-65-4 N-<4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-2-yl>benzoyl>-L-glutamic acid 
• 139577-60-9 N-<4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-2-en-2-yl>benzoyl>-L-glutamic acid 

Relevant articles and documents

Synthesis of 10-substituted "open-chain" analogues of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF, lometrexol)

Several novel and very potent folate antimetabolites, structurally based upon our previously described "open-chain" version of DDATHF but carrying 1-carbon substituents in the 10-position, have been synthesized. A key synthetic sequence involving a pallad