1396689-72-7Relevant articles and documents
Carbene-Catalyzed Dynamic Kinetic Resolution of Carboxylic Esters
Chen, Xingkuan,Fong, Jacqueline Zi Mei,Xu, Jianfeng,Mou, Chengli,Lu, Yunpeng,Yang, Song,Song, Bao-An,Chi, Yonggui Robin
supporting information, p. 7212 - 7215 (2016/07/06)
Carbene-catalyzed reaction of carboxylic esters has the potential to offer effective synthetic solutions that cannot be readily achieved by using the more conventional aldehyde-Type substrates. Here we report the first carbene-catalyzed dynamic kinetic resolution of α,α-disubstituted carboxylic esters with up to 99:1 er and 99% yield. The present study clearly illustrates the unique power of carbene-catalyzed reactions of readily available and easy to handle carboxylic esters.
Remarkable improvement achieved by imidazole derivatives in ruthenium-catalyzed hydroesterification of alkenes using formates
Konishi, Hideyuki,Muto, Takashi,Manabe, Kei,Ueda, Tsuyoshi
supporting information, p. 4722 - 4725,4 (2012/12/12)
Imidazole derivatives are revealed to be effective ligands in the Ru-catalyzed hydroesterification of alkenes using formates, affording one-carbonelongated esters in high yields. Further, intramolecular hydroesterification was successfully performed to give lactones for the first time. Imidazole derivatives can contribute to promote the reaction as well as to suppress the undesired decarbonylation of formate. Toxic CO gas, a directing group, and large excess alkenes are not required.
