139756-24-4

Basic information

• Product Name: Benzenesulfonyl chloride, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl )-4-propoxy-
• CAS NO: 139756-24-4
• Molecular Formula: C18H21ClN4O4S
• Molecular Weight: 424.908
• Mol File: 139756-24-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenesulfonyl chloride, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl )-4-propoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonyl chloride, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl )-4-propoxy-(139756-24-4)
• EPA Substance Registry System: Benzenesulfonyl chloride, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl )-4-propoxy-(139756-24-4)

Safety Data

• Hazardous Substances Data: 139756-24-4(Hazardous Substances Data)

Usage

General Description

Benzenesulfonyl chloride, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxy- is a chemical compound that belongs to the class of sulfonyl chlorides. It consists of a benzene ring attached to a sulfonyl chloride functional group, as well as a substituted pyrazolo[4,3-d]pyrimidine ring with a propoxy group. Benzenesulfonyl chloride, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl )-4-propoxy- is often used as a reagent in organic synthesis, particularly in the formation of sulfonamides and other organic compounds. It can also be utilized as an intermediate in the production of pharmaceuticals and agrochemicals. Additionally, it may have bioactive properties and is of interest in medicinal chemistry research.

Upstream product

• 139756-23-3 5-(2-n-propoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 
• 139756-04-0 1-Methyl-4-(2-n-propoxybenzamido)-3-n-propylpyrazole-5-carboxamide 

Downstream Products

• 268203-93-6 5-[2-propyloxy-5-[2-(1-methyl-2-pyrrolidinyl)ethylaminosulfonyl]phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-one 

Relevant articles and documents

Preparation method for heterocyclic compounds

The invention specifically relates to a preparation method for heterocyclic compounds with udenafil as a representative, belonging to the field of chemical pharmaceutical technology. The invention aims to overcome the technical problems of high production cost, low yield, great treatment quantities of waste acid and exhaust gas and potential safety hazards in conventional synthetic methods. To overcome the technical problems, the invention provides the preparation method for the heterocyclic compounds. The preparation method comprises the following steps: 1, subjecting a starting raw materialA to a reaction under the action of an organic solvent and alkali to produce an intermediate 1; 2, reacting the intermediate 1 with a sulfonating agent to produce an intermediate 2; and 3, reacting the intermediate 2 with a starting raw material B in an organic solvent to obtain a finished compound as shown in a formula I. The preparation method provided by the invention uses easily available andcheap raw materials, avoids usage of expensive coupling reagents, improves the selectivity of next-step sulfonation, and is high in product yield and purity, mild in reaction conditions and beneficialfor scaled-up production in workshops.