1398048-30-0

Basic information

• Product Name: C₂₁H₃₃FN₂O₄Si
• Synonyms: C₂₁H₃₃FN₂O₄Si
• CAS NO: 1398048-30-0
• Molecular Weight: 424.588
• Mol File: 1398048-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₃₃FN₂O₄Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₃₃FN₂O₄Si(1398048-30-0)
• EPA Substance Registry System: C₂₁H₃₃FN₂O₄Si(1398048-30-0)

Safety Data

• Hazardous Substances Data: 1398048-30-0(Hazardous Substances Data)

Upstream product

• 45347-82-8 azetidine-3-ol 
• 1398048-27-5 C₁₅H₁₉FN₂O₄ 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1398048-32-2 C₂₁H₃₅FN₂O₂Si 
• 1398048-34-4 C₂₅H₄₀FN₃O₂Si 
• 1398045-97-0 3-fluoro-4-(3-{3-fluoro-4-[4-(4-hydroxy-piperidin-1-yl)-4-oxo-butyl]-phenyl}-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl)-2-trifluoromethyl-benzonitrile 
• 1398045-99-2 4-(3-{3-fluoro-4-[4-(4-hydroxy-piperidin-1-yl)-4-oxo-butyl]-phenyl}-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl)-2-trifluoromethyl-benzonitrile 
• 1398048-40-2 C₁₉H₂₇FN₄O 
• 1398046-01-9 3-fluoro-4-(3-{3-fluoro-4-[4-(4-methyl-piperazin-1-yl)-4-oxo-butyl]-phenyl}-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl)-2-trifluoromethyl-benzonitrile 
• 1398046-03-1 4-(3-{3-fluoro-4-[4-(4-methyl-piperazin-1-yl)-4-oxo-butyl]-phenyl}-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl)-2-trifluoromethyl-benzonitrile 

Relevant articles and documents

ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF

Disclosed are substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds. The compounds and compositions can be used for treatment of androgen receptor-associated diseases or disorders, such as prostate cancer, benign prostatic hypertrophy, male hair loss and hypertrichosis.