1398113-16-0

Basic information

• Product Name: C₁₄H₁₆N₄
• Synonyms: C₁₄H₁₆N₄
• CAS NO: 1398113-16-0
• Molecular Weight: 240.308
• Mol File: 1398113-16-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₆N₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₆N₄(1398113-16-0)
• EPA Substance Registry System: C₁₄H₁₆N₄(1398113-16-0)

Safety Data

• Hazardous Substances Data: 1398113-16-0(Hazardous Substances Data)

Upstream product

• 1398113-15-9 C₁₅H₁₇N₃S 
• 1398113-14-8 C₁₅H₁₅N₃O₂S 
• 1398113-13-7 C₁₄H₁₃N₃O₂S 
• 1398113-12-6 C₁₄H₁₃N₃O₃ 
• 1398113-11-5 C₁₆H₁₉N₃O₄ 
• 1398113-04-6 C₂₄H₂₅BrN₂O₄ 
• 1398113-02-4 C₁₇H₁₆BrNO₅S 
• 1398113-01-3 C₁₇H₁₆BrNO₄S 
• 1398113-00-2 C₁₇H₁₈BrNO₃ 
• 1183581-39-6 (RS)-2-amino-2-(3-bromo-phenyl)-propionic acid methyl ester 
• 1183013-69-5 (RS)-2-amino-2-(3-bromo-phenyl)-propan-1-ol 
• 953741-63-4 rac-2-amino-2-(3-bromo-phenyl)-propionitrile 
• 2142-63-4 1-(3-Bromophenyl)ethanone 

Downstream Products

• 1398112-67-8 rac-5-methoxy-pyrazine-2-carboxylic acid [3-(1-amino-3-methyl-3,4-dihydro-pyrrolo[1,2-a]pyrazin-3-yl)-phenyl]-amide 

Relevant articles and documents

3,4-DIHYDRO-PYRROLO[1,2-a]PYRAZIN-1-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)

The present invention relates to novel 3,4-dihydro-pyrrolo[l,2-a]pyrazin-1-ylamine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease or dementia associated with beta-amyloid.