1398584-52-5

Basic information

• Product Name: methyl 3-({[(1R)-1-(2,4-difluorophenyl)propyl](isoquinolin-3-ylcarbonyl)amino}methyl)benzoate
• Synonyms: methyl 3-({[(1R)-1-(2,4-difluorophenyl)propyl](isoquinolin-3-ylcarbonyl)amino}methyl)benzoate
• CAS NO: 1398584-52-5
• Molecular Weight: 474.507
• Mol File: 1398584-52-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-({[(1R)-1-(2,4-difluorophenyl)propyl](isoquinolin-3-ylcarbonyl)amino}methyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-({[(1R)-1-(2,4-difluorophenyl)propyl](isoquinolin-3-ylcarbonyl)amino}methyl)benzoate(1398584-52-5)
• EPA Substance Registry System: methyl 3-({[(1R)-1-(2,4-difluorophenyl)propyl](isoquinolin-3-ylcarbonyl)amino}methyl)benzoate(1398584-52-5)

Safety Data

• Hazardous Substances Data: 1398584-52-5(Hazardous Substances Data)

Upstream product

• 6624-49-3 isoquinoline-3-carboxylic acid 
• 1398583-72-6 C₁₈H₁₉F₂NO₂ 

Relevant articles and documents

ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS TRPM8 MODULATORS

The invention provides a compound of the formula (I): wherein A, R1, R2 and R3 are as defined herein, or a pharmaceutically acceptable salt thereof. Such compounds are small molecule TRPM8 blockers and therefore useful in the propylaxis or treatment of a wide range of diseases, conditions or syndromes, including cold allodynia and Raynaulds syndrome.