1399849-96-7

Basic information

• Product Name: methyl 4-bromo-2-(3-methoxypropoxy)benzoate
• Synonyms: methyl 4-bromo-2-(3-methoxypropoxy)benzoate
• CAS NO: 1399849-96-7
• Molecular Weight: 303.153
• Mol File: 1399849-96-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 4-bromo-2-(3-methoxypropoxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-bromo-2-(3-methoxypropoxy)benzoate(1399849-96-7)
• EPA Substance Registry System: methyl 4-bromo-2-(3-methoxypropoxy)benzoate(1399849-96-7)

Safety Data

• Hazardous Substances Data: 1399849-96-7(Hazardous Substances Data)

Upstream product

• 1248956-68-4 4-bromo-2-(3-methoxypropoxy)benzoic acid 
• 74-88-4 methyl iodide 
• 112704-79-7 2-fluoro-4-bromobenzoic acid 
• 36865-41-5 3-bromopropanol methyl ether 
• 22717-56-2 4-bromo-2-Hydroxybenzoic Acid Methylester 
• 1666-28-0 4-bromosalicylic acid 

Downstream Products

• 1399849-97-8 methyl 4-acetyl-2-(3-methoxypropoxy)benzoate 

Relevant articles and documents

Development of DHQ-based chemical biology probe to profile cellular targets for HBV

Chronic hepatitis B virus (HBV) infection has been a serious public health burden worldwide. Current anti-HBV therapies could not eliminate HBV ultimately. Considering the characteristics of HBV, it is impossible to be entirely cured based on current therapies. Therefore, it is urgently needed to develop novel therapeutic agents with new mechanism of action. The dihydroquinolizinone (DHQ) derivatives exhibited potent anti-HBV activity by decreasing HBV DNA and HBsAg level in an obscure mechanism of action. In this study, we have optimized the DHQ scaffold, developed the photoaffinity probe, with which to identify potential binding proteins.

NOVEL RENIN INHIBITOR

The present invention provides a nitrogen-containing saturated heterocyclic compound of the formula [I] which is useful as a renin inhibitor. wherein R1 is a cycloalkyl group or an alkyl, R22 is an optionally substituted aryl and the like, R is a lower alkyl group, R3, R4, R5 and R6 are the same or different, and are a hydrogen atom, an optionally substituted carbamoyl, an optionally substituted alkyl, or alkoxycarbonyl, or a pharmaceutically acceptable salt thereof.