140173-57-5

Basic information

• Product Name: 3H-Pyrazole, 3,3-dimethyl-5-phenyl-4-(phenylethynyl)-
• CAS NO: 140173-57-5
• Molecular Formula: C19H16N2
• Molecular Weight: 272.349
• Mol File: 140173-57-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3H-Pyrazole, 3,3-dimethyl-5-phenyl-4-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrazole, 3,3-dimethyl-5-phenyl-4-(phenylethynyl)-(140173-57-5)
• EPA Substance Registry System: 3H-Pyrazole, 3,3-dimethyl-5-phenyl-4-(phenylethynyl)-(140173-57-5)

Safety Data

• Hazardous Substances Data: 140173-57-5(Hazardous Substances Data)

Upstream product

• 5281-20-9 acetone hydrazone 
• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 536-74-3 phenylacetylene 
• 1719-19-3 2-Methyl-4-phenyl-3-butyn-2-ol 
• 2684-60-8 2-diazopropane 

Downstream Products

• 140173-59-7 3,3,3',3'-tetramethyl-4',5'-diphenyl-4,5'-bi-3H-pyrazolyl 
• 140173-55-3 3,3-dimethyl-5-phenyl-4-phenylethynylcyclopropene 

Relevant articles and documents

Iron(III) Chloride Catalyzed Nucleophilic Substitution of Tertiary Propargylic Alcohols and Synthesis of Iodo-3H-Pyrazoles

A straightforward and concise method was developed for the efficient and rapid synthesis of iodo-3H-pyrazoles by the FeCl3/I2-mediated propargylic substitution of tertiary propargylic alcohols with p-toluenesulfonyl hydrazide and subsequent cyclization under mild conditions. The method constitutes a novel approach to the synthesis of various iodo-3H-pyrazoles with a wide substrate scope and in high yields.