1402883-29-7

Basic information

• Product Name: ethyl 3-oxo-3-((1S,2R)-2-phenylcyclopropyl)propanoate
• Synonyms: ethyl 3-oxo-3-((1S,2R)-2-phenylcyclopropyl)propanoate
• CAS NO: 1402883-29-7
• Molecular Weight: 232.279
• Mol File: 1402883-29-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 3-oxo-3-((1S,2R)-2-phenylcyclopropyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-oxo-3-((1S,2R)-2-phenylcyclopropyl)propanoate(1402883-29-7)
• EPA Substance Registry System: ethyl 3-oxo-3-((1S,2R)-2-phenylcyclopropyl)propanoate(1402883-29-7)

Safety Data

• Hazardous Substances Data: 1402883-29-7(Hazardous Substances Data)

Upstream product

• 140-29-4 phenylacetonitrile 
• 96847-52-8 (1R,2S)-2-oxo-1-phenyl-3-oxabicyclo[3.1.0]hexane 
• 29667-46-7 (1S,2R)-2-phenylcyclopropylmethanol 
• 186183-64-2 (1S,2R)-1-formyl-2-phenylcyclopropane 
• 23020-18-0 (1S,2R)-2-phenylcyclopropanecarboxylic acid 
• 6148-64-7 ethyl potassium malonate 

Downstream Products

• 1402883-28-6 2-amino-3-methyl-6-((1R,2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one 
• 1402883-27-5 2-amino-3-methyl-6-((1S,2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one 
• 1402883-30-0 2-amino-6-((1S,2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one 

Relevant articles and documents

CYCLOPROPANE DERIVATIVE HAVING BACE1 INHIBITING ACTIVITY

The present invention relates to compounds of the Formula (I) and (II): wherein each variable is as defined in the specification, pharmaceutically acceptable salts and solvates thereof, as well as use of such compounds as a BACE1 inhibitor. The compounds of the invention are useful as an agent for treating a disease induced by production, secretion and/or deposition of amyloid β protein.