1402933-43-0Relevant articles and documents
Aqueous-mediated michael addition of active methylene compounds with nitroalkenes
Dong, Wenkai,Xu, Dongcheng,Xie, Jianwu
, p. 1771 - 1774 (2012)
A simple, atom economical and highly efficient green protocol has been developed for the synthesis of Michael adducts of nitroalkenes and 2-amino-2-chromene derivatives by Michael addition of active methylene compounds (such as malononitrile and ethyl cyanoacetate) to nitroalkenes under aqueous-mediated conditions. This green approach provided the desired products in high yields and the reaction scope proved to be quite broad.