140372-83-4Relevant articles and documents
Iron-Catalyzed Azidoalkylthiation of Alkenes with Trimethylsilyl Azide and 1-(Alkylthio)pyrrolidine-2,5-diones
Yu, Jipan,Jiang, Min,Song, Zhixuan,He, Tiancheng,Yang, Haijun,Fu, Hua
, p. 2806 - 2810 (2016)
A simple, efficient and practical iron-catalyzed azidoarylthiation of alkenes has been developed at room temperature, and the corresponding products containing ortho-sited sulfide and azide units were obtained in moderate to good yields with good tolerance of functional groups. The protocol uses readily available 1-(alkylthio)pyrrolidine-2,5-diones and trimethylsilyl azide as the alkylthiation and azidation reagents, respectively, inexpensive and environmentally friendly iron chloride as the catalyst without addition of any ligand and additive. (Figure presented.).
Synthesis of mexiletine analogues from non-activated aziridines
Ingebrigtsen, Truls,Lejon, Tore
, p. 891 - 902 (2008/03/13)
A general method for the synthesis of mexiletine analogues by nucleophilic ring opening of non-activated racemic aziridines has been developed (Scheme 1). Structural variation is introduced by employing different nucleophiles or by altering the substitution on the aziridine ring.
Base-promoted aminoethylation of thiols with 2-oxazolidinones: A simple synthesis of 2-aminoethyl sulfides
Ishibashi, Hiroyuki,Uegaki, Masayuki,Sakai, Manami,Takeda, Yoshifumi
, p. 2115 - 2120 (2007/10/03)
A simple synthesis of 2-aminoethyl sulfides using a base-promoted reaction of 2-oxazolidinones with thiols is described. An application of this method to the synthesis of chiral 2-aminoethyl sulfides and sulfur-containing heterocyclic compounds is also presented.
