1408234-32-1

Basic information

• Product Name: (2R,3R,4S)-diethyl 2-(benzo[d][1,3]dioxol-5-yl)-4-(2-methoxy-2-oxoethyl)-3-nitrocyclohexane-1,1-dicarboxylate
• Synonyms: (2R,3R,4S)-diethyl 2-(benzo[d][1,3]dioxol-5-yl)-4-(2-methoxy-2-oxoethyl)-3-nitrocyclohexane-1,1-dicarboxylate
• CAS NO: 1408234-32-1
• Molecular Weight: 465.457
• Mol File: 1408234-32-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S)-diethyl 2-(benzo[d][1,3]dioxol-5-yl)-4-(2-methoxy-2-oxoethyl)-3-nitrocyclohexane-1,1-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S)-diethyl 2-(benzo[d][1,3]dioxol-5-yl)-4-(2-methoxy-2-oxoethyl)-3-nitrocyclohexane-1,1-dicarboxylate(1408234-32-1)
• EPA Substance Registry System: (2R,3R,4S)-diethyl 2-(benzo[d][1,3]dioxol-5-yl)-4-(2-methoxy-2-oxoethyl)-3-nitrocyclohexane-1,1-dicarboxylate(1408234-32-1)

Safety Data

• Hazardous Substances Data: 1408234-32-1(Hazardous Substances Data)

Upstream product

• 1485-00-3 5-(2-nitrovinyl)benzo[1,3]dioxole 
• 17171-26-5 4-Methoxycarbonyl-buten-⁽³⁾-yl-⁽¹⁾-malonsaeurediaethylester 

Relevant articles and documents

Concise construction of the tetracyclic core of lycorine-type alkaloids and the formal synthesis of α-lycorane based on asymmetric bifunctional thiourea-catalyzed cascade reaction

A concise and stereoselective construction of the tetracyclic core of lycorine-type alkaloids and the formal synthesis of α-lycorane has been achieved. The feature of the current method is the employment of a bifunctional thiourea-catalyzed cascade reaction as a powerful tool to construct the skeleton of the natural product, which is a challenging yet very rarely explored strategy. As a result, the tetracyclic core is efficiently synthesized in just three simple operations involving two consecutive cascade reactions. The Royal Society of Chemistry 2012.