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1408323-52-3

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1408323-52-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1408323-52-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,8,3,2 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1408323-52:
(9*1)+(8*4)+(7*0)+(6*8)+(5*3)+(4*2)+(3*3)+(2*5)+(1*2)=133
133 % 10 = 3
So 1408323-52-3 is a valid CAS Registry Number.

1408323-52-3Relevant articles and documents

Synthesis and in vitro anti-Toxoplasma gondii activity of a new series of aryloxyacetophenone thiosemicarbazones

Ansari, Mahsa,Montazeri, Mahbobeh,Daryani, Ahmad,Farshadfar, Kaveh,Emami, Saeed

, p. 1223 - 1234 (2019/09/09)

Abstract: A new series of aryloxyacetophenone thiosemicarbazones 4a–q have been synthesized as anti-Toxoplasma gondii agents. All compounds showed significant inhibitory activity against T. gondii-infected cells (IC50 values 1.09–25.19?μg/mL). The 4-fluorophenoxy derivative (4l) was the most potent compound with the highest selectivity toward host cells (SI = 19), being better than standard drug pyrimethamine. SAR study indicated that the concurrence of proper substituents on both aryl ring of phenoxyacetophenone is important for potency and safety profile. Further in vitro experiments with the representative compounds 4l and 4p revealed that these compounds at the concentration of 5?μg/mL can significantly reduce the viability of T. gondii tachyzoites, as well as their infectivity rate and intracellular proliferation, comparable to those of pyrimethamine. Graphic abstract: [Figure not available: see fulltext.]

Replacement of the Methylene of Dihydrochalcones with Oxygen: Synthesis and Biological Evaluation of 2-Phenoxyacetophenones

Ansari, Mahsa,Emami, Saeed,Khalilzadeh, Mohammad A.,Maghsoodlou, Malek T.,Foroumadi, Alireza,Faramarzi, Mohammad A.,Samadi, Nasrin,Ardestani, Sussan K.

, p. 591 - 597 (2012/11/07)

With the aim of finding new bioactive compounds, a series of phenoxyacetophenone derivatives 2 were designed and synthesized as oxygen analogs of dihydrochalcones. Also, phenoxyacetophenones were converted to (Z)-oxime derivatives 3 and their geometry wer

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