14097-41-7

Basic information

• Product Name: 5-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-
• Synonyms: 2-Methyl-1,2,3,4-tetrahydro-[5]isochinolylamin;2-methyl-5-amino-1,2,3,4-tetrahydroisoquinoline;2-methyl-1,2,3,4-tetrahydro-[5]isoquinolylamine;5-amino-2-methyl-1,2,3,4-tetrahydro isoquinoline
• CAS NO: 14097-41-7
• Molecular Formula: C10H14N2
• Molecular Weight: 162.23200
• Mol File: 14097-41-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 75 °C
• Boiling Point: 139-142 °C(Press: 0.1 Torr)
• Density: 1.084±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-(14097-41-7)
• EPA Substance Registry System: 5-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-(14097-41-7)

Safety Data

• Hazardous Substances Data: 14097-41-7(Hazardous Substances Data)

Upstream product

• 54410-11-6 2-methyl-5-nitro isoquinolinium methyl sulphate 
• 1125-60-6 isoquinolin-5-ylamine 
• 69062-43-7 2-methyl-5-nitro-1,2,3,4-tetrahydro-isoquinoline 
• 19384-71-5 5-amino-2-methylisoquinolinium iodide 
• 1612-65-3 2-methyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 14097-42-8 5-Hydroxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 27461-31-0 3,4,5-trimethoxy-N-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide 
• 37481-45-1 5-(2-bromobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-42-8 5-(2,6-diethylbenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-39-3 5-(2,6-dimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-37-1 5-(2-Fluorobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-36-0 5-(2-Chlorobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-44-0 5-(2-iodobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-41-7 5-(2,6-dimethylbenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-38-2 4-methoxy-N-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide 
• 37481-43-9 5-(2-nitrobenzamido)-2-methyl - 1,2,3,4-tetrahydroisoquinoline 
• 201149-95-3 N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-4-ethyl-2-methoxybenzamide, Hydrochloride 
• 201149-91-9 N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-4-iso-propyl-2-methoxybenzamide, hydrochloride 
• 201149-80-6 N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-4-ethyl-2-methoxy-5-chlorobenzamide, hydrochloride 

Relevant articles and documents

THERAPEUTIC METHODS AND COMPOUNDS

The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria.

Identification of a series of 1,2,3,4-tethydroisoquinolinylbenzamides with potential anticonvulsant activity

A series of N-(tetrahydroisoquinolinyl)-2-methoxybenzamides was identified by high-throughput screening at the novel SB-204269 binding site. SAR studies have provided compounds 4 and 14 with high affinity and good anticonvulsant activity in animal models.

Isatinoxime derivatives, their preparation and use

A compound having the formula STR1 wherein R 4 and R 5 independently are hydrogen, halogen, CF 3, CN, NO 2 or SO 2 NR 1 R 2 whereinR 1 is hydrogen or straight, C 1-6 -alkyl which may be branched or cyclic,R 2 is hydrogen or straight, C 1-6 -alkyl which ma