1411711-52-8

Basic information

• Product Name: (dl)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone
• Synonyms: (dl)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone
• CAS NO: 1411711-52-8
• Molecular Weight: 284.743
• Mol File: 1411711-52-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (dl)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone(CAS DataBase Reference)
• NIST Chemistry Reference: (dl)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone(1411711-52-8)
• EPA Substance Registry System: (dl)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone(1411711-52-8)

Safety Data

• Hazardous Substances Data: 1411711-52-8(Hazardous Substances Data)

Upstream product

• 106-89-8 epichlorohydrin 
• 438056-69-0 4-(4-aminophenyl)morpholin-3-one 

Downstream Products

• 1411711-56-2 4-{4-[5-chloromethyl-2-oxo-1,3-oxazoIidine-3-yl]-phenyl}-morpholine-3-one 
• 366789-02-8 Rivaroxaban 
• 1411775-03-5 4-{4-[5-[(dibenzylamino)methyl]-2-oxo-1,3-oxazolidine-3-yl]phenyl}morpholine-3-one 
• 1411711-60-8 4-{4-[5-iodomethyl-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morpholine-3-one 
• 1411775-04-6 4-{4-[5-aminomethyl-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morpholine-3-one formate 
• 1411711-66-4 4-{4-[5-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate 
• 1265682-11-8 rac-4-[4-[5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one 
• 482306-32-1 5-chloro-N-({(5)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide 
• 482305-98-6 (dl)-5-chloro-N-[2-hydroxy-3-[[4-(3-oxo-4-morpholino)phenyl]amino]propyl]-2-thiophenecarboxamide 

Relevant articles and documents

Stereocontrolled, Divergent, Al(lll)-Catalyzed Coupling of Chiral N-Aryl Epoxy Amines and CO2

A divergent coupling reaction was achieved between N-aryl epoxy amines and CO2. By using two different cocatalysts, tetrabutylammonium iodide (TBAI) or 4-dimethylaminopyridine (DMAP) together with an Al(III) Lewis acid, cyclic carbonates or oxazolidinones were selectively produced through two distinct reaction pathways, respectively. The proposed reaction mechanism was supported by the stereochemical determination of the products. A gram-scale production of Linezolid was successfully achieved.