1411775-00-2

Basic information

• Product Name: 4-(4-{[(2R)-3-(dibenzylamino)-2-hydroxypropyl]amino}phenyl)morpholin-3-one
• Synonyms: 4-(4-{[(2R)-3-(dibenzylamino)-2-hydroxypropyl]amino}phenyl)morpholin-3-one
• CAS NO: 1411775-00-2
• Molecular Weight: 445.561
• Mol File: 1411775-00-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-{[(2R)-3-(dibenzylamino)-2-hydroxypropyl]amino}phenyl)morpholin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-{[(2R)-3-(dibenzylamino)-2-hydroxypropyl]amino}phenyl)morpholin-3-one(1411775-00-2)
• EPA Substance Registry System: 4-(4-{[(2R)-3-(dibenzylamino)-2-hydroxypropyl]amino}phenyl)morpholin-3-one(1411775-00-2)

Safety Data

• Hazardous Substances Data: 1411775-00-2(Hazardous Substances Data)

Upstream product

• 565176-84-3 (S)-N,N-dibenzylamino-1-(oxiran-2-ylmethyl)methylamine 
• 438056-69-0 4-(4-aminophenyl)morpholin-3-one 
• 103-49-1 dibenzylamine 
• 1236384-02-3 (S)-3-chloro-2-hydroxypropyl dibenzylamine 

Downstream Products

• 1372665-04-7 4-{4-[(5S)-5-((dibenzylamino)methyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one 
• 446292-10-0 4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one 
• 366789-02-8 Rivaroxaban 

Relevant articles and documents

A the advantage cuts down Sha Ban method for the preparation of intermediates thereof, and intermediate compound

The present invention discloses a preparation method for a rivaroxaban intermediate compound represented by a formula 5, wherein the preparation method comprises the following steps: carrying out a benzyl group removing reaction of a compound 4 in a solvent to prepare a compound 5. The present invention further discloses a rivaroxaban preparation method and intermediate compounds. According to the preparation method, chiral raw materials are easy to obtain, and have cheap price, the process is simple, the post treatment is simple, the intermediate and the final product are easy to purify, the total yield is high, the purity is high, and industrial production is easily achieved.