141294-37-3Relevant articles and documents
Step-efficient access to chiral primary amines
Nugent, Thomas C.,Marinova, Sofiya M.
, p. 153 - 166 (2013/02/25)
Routes to enantioenriched amines are outlined that employ reductive amination and carbanion addition methods. The strategies require either one or two reaction steps from prochiral carbonyl compounds for the synthesis of the corresponding chiral primary amines. Georg Thieme Verlag Stuttgart New York.
Asymmetric reductive amination: Convenient access to enantioenriched alkyl-alkyl or aryl-alkyl substituted α-chiral primary amines
Nugent, Thomas C.,Ghosh, Abhijit K.,Wakchaure, Vijay N.,Mohanty, Rashmi R.
, p. 1289 - 1299 (2007/10/03)
A two-step procedure for producing optically active, high value primary amines has been developed. The first and key step is the asymmetric reductive amination of a prochiral alkyl alkyl (acyclic or cyclic) or aryl alkyl (acyclic or cyclic) ketone with (R
Asymmetric reduction of enantiopure imines with zinc borohydride: Stereoselective synthesis of chiral amines
Cimarelli, Cristina,Palmieri, Gianni
, p. 2555 - 2563 (2007/10/03)
The first application of zinc borohydride in the reduction of enantiopure imines for the stereoselective preparation of both the enantiomers of secondary amines is described. A possible explanation of the stereoselectivity and of the reaction mechanism is