1412975-11-1

Basic information

• Product Name: (1aRS,7bSR)-5-{2-[((R)-1-ethylpyrrolidin-3-ylmethyl)amino]benzene-sulfonylamino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid
• Synonyms: (1aRS,7bSR)-5-{2-[((R)-1-ethylpyrrolidin-3-ylmethyl)amino]benzene-sulfonylamino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid
• CAS NO: 1412975-11-1
• Molecular Weight: 471.577
• Mol File: 1412975-11-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1aRS,7bSR)-5-{2-[((R)-1-ethylpyrrolidin-3-ylmethyl)amino]benzene-sulfonylamino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1aRS,7bSR)-5-{2-[((R)-1-ethylpyrrolidin-3-ylmethyl)amino]benzene-sulfonylamino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid(1412975-11-1)
• EPA Substance Registry System: (1aRS,7bSR)-5-{2-[((R)-1-ethylpyrrolidin-3-ylmethyl)amino]benzene-sulfonylamino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid(1412975-11-1)

Safety Data

• Hazardous Substances Data: 1412975-11-1(Hazardous Substances Data)

Upstream product

• 199174-29-3 tert-butyl (R)-3-(aminomethyl)pyrrolidine-1-carboxylate 
• 879275-54-4 tert-butyl (R)-3-(N-benzyloxycarbonyl)aminomethylpyrrolidine-1-carboxylate 
• 1412978-43-8 tert-butyl (S)-3-[N-benzyl-N-(benzyloxycarbonyl)aminomethyl]pyrrolidine-1-carboxylate 
• 1412978-41-6 benzyl N-((S)-pyrrolidin-3-ylmethyl)-N-benzylcarbamate 
• 1412978-39-2 benzyl N-((S)-1-acetylpyrrolidin-3-ylmethyl)-N-benzylcarbamate 
• 1412978-37-0 ((R)-1-acetylpyrrolidin-3-ylmethyl)amine 
• 1412978-35-8 ((R)-1-ethylpyrrolidin-3-yl)methyl-amine 

Relevant articles and documents

METHODS OF TREATING LIVER DISEASES

The invention provides tricyclic compounds and their use in treating liver disorders, such as non-alcoholic steatohepatitis and related disorders (e.g., fibrosis). The compounds are contemplated to have activity against methionyl aminopeptidase 2.