141329-77-3Relevant articles and documents
Highly Diastereoselective Alcoholysis of ?-Symmetric Dicarboxylic Acid Anhydrides Using 1-Phenyl-3,3-bis(trifluoromethyl)propan-1,3-diol
Suda, Yoshimitsu,Yago, Seiji,Shiro, Motoo,Taguchi, Takeo
, p. 389 - 392 (2007/10/02)
Highly diastereoselective alcoholysis of ?-symmetric dicarboxylic acid anhydrides was performed using 1-phenyl-3,3-bis(trifluoromethyl)propan-1,3-diol.The importance of the geminally trifluoromethylated carbinol moiety for achieving a high degree of chiral induction was confirmed from lower diastereoselectivity with the hydroxyl protected 1,3-diol or with the similar 1,3-diols having hydrocarbon substituents instead of the trifluoromethyl group.