1413809-77-4

Basic information

• Product Name: tert-butyl furan-2-yl(2-hydroxy-2-(phenylethynyl)octyl)-carbamate
• CAS NO: 1413809-77-4
• Molecular Weight: 411.541
• Mol File: 1413809-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl furan-2-yl(2-hydroxy-2-(phenylethynyl)octyl)-carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl furan-2-yl(2-hydroxy-2-(phenylethynyl)octyl)-carbamate(1413809-77-4)
• EPA Substance Registry System: tert-butyl furan-2-yl(2-hydroxy-2-(phenylethynyl)octyl)-carbamate(1413809-77-4)

Safety Data

• Hazardous Substances Data: 1413809-77-4(Hazardous Substances Data)

Upstream product

• 66222-29-5 tri-n-butylstannylmethyl iodide 
• 160254-75-1 1-phenyl-1-nonyn-3-one 
• 56267-47-1 tert-butyl furan-2-ylcarbamate 

Downstream Products

• 1413810-45-3 3-hexyl-4-phenyl-1H-indol-5-ol 

Relevant articles and documents

5-hydroxyindoles by intramolecular alkynol-furan diels-alder cycloaddition

A convergent approach provides a convenient access to synthetically and biologically useful 3,4-disubstituted 5-hydroxyindoles. The one-pot procedure uses microwave heating to initiate an intramolecular [4 + 2]-cycloaddition of an alkynol segment onto a furan followed by a fragmentation, aromatization, and N-Boc deprotection cascade. Yields range from 15 to 74%, with aromatic substituents providing better conversions. 4-Trimethylsilylated analogues undergo a 1,3-silatropic rearrangement to give the O-TMS ethers.