1415011-16-3

Basic information

• Product Name: (S)-6-bromo-1-ethynyl-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalene
• Synonyms: (S)-6-bromo-1-ethynyl-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalene
• CAS NO: 1415011-16-3
• Molecular Weight: 375.264
• Mol File: 1415011-16-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-6-bromo-1-ethynyl-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-6-bromo-1-ethynyl-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalene(1415011-16-3)
• EPA Substance Registry System: (S)-6-bromo-1-ethynyl-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalene(1415011-16-3)

Safety Data

• Hazardous Substances Data: 1415011-16-3(Hazardous Substances Data)

Upstream product

• 1415011-15-2 (S)-((6-bromo-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalen-1-yl)ethynyl)trimethylsilane 
• 5876-76-6 (R)-4-phenylbut-3-yn-2-ol 
• 1415011-14-1 6-bromo-1-((trimethylsilyl)ethynyl)naphthalen-2-ol 
• 591-50-4 iodobenzene 
• 102153-45-7 6-bromo-1-iodonaphthalen-2-ol 
• 15231-91-1 6-bromo-naphthalen-2-ol 

Downstream Products

• 1415011-17-4 (S)-tert-butyl (3-((6-bromo-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalen-1-yl)ethynyl)pyridin-4-yl)carbamate 
• 1415011-19-6 C₃₂H₂₅BrN₂O 
• 1415011-18-5 (S)-tert-butyl (3-((6-bromo-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalen-1-yl)ethynyl)pyridin-4-yl)(pent-2-yn-1-yl)carbamate 
• 1415011-20-9 (S)-3-((6-bromo-2-((4-phenylbut-3-yn-2-yl)oxy)naphthalen-1-yl)ethynyl)-N-methyl-N-(pent-2-yn-1-yl)pyridin-4-amine 

Relevant articles and documents

Point-to-helical chirality transfer for a scalable and resolution-free synthesis of a helicenoidal DMAP organocatalyst

The synthesis of a second-generation [6]-helicenoidal DMAP organocatalyst is reported. The synthesis is reliant upon a highly diastereoselective Rh-catalysed [2 + 2 + 2] triyne cycloisomerization, using an existing stereocentre to control the sense of forming helicity. Taken together, a scalable (>1 g), resolution-free entry to a helical DMAP with the capacity for subsequent functionalization, has been achieved.