1415226-38-8

Basic information

• Product Name: 5-(3-chlorophenyl)-3-chloro-2-cyanopyridine
• Synonyms: 5-(3-chlorophenyl)-3-chloro-2-cyanopyridine
• CAS NO: 1415226-38-8
• Molecular Weight: 249.099
• Mol File: 1415226-38-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-(3-chlorophenyl)-3-chloro-2-cyanopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-chlorophenyl)-3-chloro-2-cyanopyridine(1415226-38-8)
• EPA Substance Registry System: 5-(3-chlorophenyl)-3-chloro-2-cyanopyridine(1415226-38-8)

Safety Data

• Hazardous Substances Data: 1415226-38-8(Hazardous Substances Data)

Upstream product

• 16063-70-0 2,3,5-trichloropyridine 
• 823-56-3 2-Fluoro-3,5-dichloropyridine 
• 63503-60-6 3-chlorophenylboronic acid 
• 85331-33-5 2-Cyano-3,5-dichloropyridine 

Downstream Products

• 1415226-40-2 5-(3-chlorophenyl)-3-hydroxypyridine-2-carboxylic acid 
• 1415226-39-9 5-(3-chlorophenyl)-3-methoxy-2-cyanopyridine 
• 1000025-36-4 5-(3-chlorophenyl)-3-hydroxy-pyridine-2-carboxylic acid carbamoylmethyl-amide 
• 1000025-07-9 {[5-(3-chloro-phenyl)-3-hydroxy-pyridine-2-carbonyl]-amino}-acetic acid 

Relevant articles and documents

MANUFACTURING PROCESS FOR 3,5-DICHLOROPICOLINONITRILE FOR SYNTHESIS OF VADADUSTAT

Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the syn

PROCESS FOR PREPARING 2-[[5-(3-CHLOROPHENYL)-3-HYDROXYPYRIDINE-2-CARBONYL]AMINO]ACETIC ACID

Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.

PROCESS FOR PREPARING [(3-HYDROXYPYRIDINE-2-CARBONYL)AMINO]ALKANOIC ACIDS, ESTERS AND AMIDES

Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]aminolacetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3-hydroxypyridine-2-carbonyl]amino}acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.