1415303-22-8

Basic information

• Product Name: (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide
• Synonyms: (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide
• CAS NO: 1415303-22-8
• Molecular Weight: 232.326
• Mol File: 1415303-22-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide(1415303-22-8)
• EPA Substance Registry System: (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide(1415303-22-8)

Safety Data

• Hazardous Substances Data: 1415303-22-8(Hazardous Substances Data)

Upstream product

• 5891-21-4 5-chloro-2-pentanone 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 1415303-32-0 (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide (S)-mandelic acid salt 

Downstream Products

• 1415303-32-0 (2S,1'S)-N-(1'-phenylethyl)-α-methylprolinamide (S)-mandelic acid salt 
• 42856-71-3 (S)-2-methylpyrrolidine-2-carboxylic acid 

Relevant articles and documents

Α-substd. provitamin optically active production of phosphorus

PROBLEM TO BE SOLVED: To provide an industrial method practically suitable for producing an optically active α-substituted prolines with short process and mild conditions.SOLUTION: A method of producing an optically active α-substituted prolines (6) includes (d) a step of obtaining an optically active N, α-substituted prolines (5) by hydrolysis of an optically active N, α-substituted proline amides (4), and (e) a step of obtaining an optically active α-substituted prolines (6) by eliminating the optically active N, and a protective group Rof the α-substituted prolines (5).