1415355-69-9

Basic information

• Product Name: C₁₇H₁₃N₃O₂
• Synonyms: C₁₇H₁₃N₃O₂
• CAS NO: 1415355-69-9
• Molecular Weight: 291.309
• Mol File: 1415355-69-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₃N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₃N₃O₂(1415355-69-9)
• EPA Substance Registry System: C₁₇H₁₃N₃O₂(1415355-69-9)

Safety Data

• Hazardous Substances Data: 1415355-69-9(Hazardous Substances Data)

Upstream product

• 28144-70-9 anthranilic acid amide 
• 76617-97-5 4-oxo-3,4-dihydroquinazoline-2-carboxamide 
• 122-78-1 phenylacetaldehyde 
• 29113-33-5 ethyl 4-oxo-3,4-dihydro-2-quinazolinecarboxylate 

Relevant articles and documents

Synthesis and configurational assignment of 1,2-dihydroimidazo[5,1-b] quinazoline-3,9-diones: Novel NMDA receptor antagonists

NMDA receptors form a major subdivision of the ionotropic glutamate receptor family that mediates excitatory synaptic transmission in the brain. Series of 1-substituted 1,2-dihydroimidazo[5,1-b]quinazolinediones were synthesized and found to have potent nanomolar activity at the glycine site of the NMDA receptor. Imidazoquinazolinediones were prepared by cyclocondensation of 4-oxo-quinazoline-2-carboxamide with aldehydes and orthoesters with good yields. The formed enantiomers were separated by chiral HPLC. The absolute configuration of pure enantiomers is elucidated by combined CD/Quantumchemical time-dependent DFT calculation method (TDDFT).